For all variants, run these commands:
cd "C:\Program Files\Softgenetics\Softgenetics Server\ga"
venv\Scripts\activate
python manage.py calculatevarianthgvs --all
if python manage.py calculatevarianthgvs --all works,
and reference dir is on a network drive,
but “C:\Program Files\Softgenetics\Softgenetics Server\Apache2\logs\error-GA.log” says reference dir is not valid,
then
create a minimum reference dir on server's local filesystem that has Base and RefSeq dir